Kolbe's reaction of phenol

When sodium salt of phenol (sodium phenoxide) is heated at about 400 K with carbon dioxide gas under a pressure of about 4-7 atmospheres and the product acidified, ortho hydroxy benzoic acid (salicylic acid) is formed as the main product.

Kolbe's reaction phenol

Saliccylic acid on actylation using acetic anhydride gives aspirin (acetyl salicylic acid).

For more reaction of phenol visit
Fries rearrangement: Reaction of phenol
Coupling Reaction of  Phenol
Reimer-Tiemann reaction of phenol


  1. The picture of Kolbe's reaction of phenol will published soon.